1. 个人简介:
汪冲,博士,副教授,植物学专业硕士生导师
教育经历:
2010-2017,博士,上海交通大学
2006-2010,学士,西北农林科技大学
工作经历:
2022至今,上海师范大学 副教授
2019-2022,上海师范大学 讲 师
2017-2019,上海交通大学 博士后
2. 主要研究方向:
[1] 植物基因编辑技术开发
[2] 基因编辑技术在水稻、花卉等植物中的应用
[3] 百合生物育种
3. 代表性科研项目:
[1]水稻减数分裂调节因子LOBA的克隆与功能分析,国家自然科学基金(青年基金),主持,2020-2022。
[2]结构特异性核酸内切酶参与水稻减数分裂过程的机制研究,博士后面上项目,主持, 2017-2019。
4. 代表性论文及著作:
论文
[1]Wang C#, Qu S, Zhang J, Fu M, Chen X, Liang W. OsPRD2 is essential for double-strand break formation, but not spindle assembly during rice meiosis. Front Plant Sci. 2023 Jan 13;13:1122202. SCI, IF=5.735.
[2]Wei C#, Wang C#, Jia M, Guo HX, Luo PY, Wang MG, Zhu JK, Zhang H. Efficient generation of homozygous substitutions in rice in one generation utilizing an rABE8e base editor. J Integr Plant Biol. 2021 Sep;63(9):1595-1599. SCI, IF=7.061.
[3]Ning Y#, Liu Q#, Wang C#, Qin E, Wu Z, Wang M, Yang K, Elesawi IE, Chen C, Liu H, Qin R, Liu B. Heat stress interferes with formation of double-strand breaks and homolog synapsis. Plant Physiol. 2021 Apr 23;185(4):1783-1797. SCI, IF=8.340.
[4]Zhang J#, Wang C#, Higgins JD, Kim YJ, Moon S, Jung KH, Qu S, Liang W. A Multiprotein Complex Regulates Interference-Sensitive Crossover Formation in Rice. SCI, Plant Physiol. 2019 Sep;181(1):221-235. IF=8.340.
[5]Wang C, Higgins JD, He Y, Lu P, Zhang D, Liang W. Resolvase OsGEN1 Mediates DNA Repair by Homologous Recombination. Plant Physiol. 2017,173:1316–1329. SCI, IF=8.340.
[6]Lei X, Ning Y, Eid Elesawi I, Yang K, Chen C, Wang C*, Liu B*. Heat stress interferes with chromosome segregation and cytokinesis during male meiosis in Arabidopsis thaliana. Plant Signal Behav. 2020 May 3;15(5):1746985. SCI, IF=2.247.
[7]曲姝颖,伍利民,张杰,梁婉琪,汪冲*.水稻减数分裂异常突变体osmd的表型分析及基因定位. 分子植物育种. 2020,18(1): 238-245.
[8]孙星,王文文,卫纯洁,路双,郑志仁,张辉,徐晨曦,汪冲*利用基因编辑技术提高番茄GABA含量的研究进展. 上海师范大学学报. 2022,51(1):87-93.
[9]Wei C, Liu H, Wang W, Luo P, Chen Q, Li R, Wang C, Botella JR, Zhang H. Expanding the Editing Window of Cytidine Base Editors With the Rad51 DNA-Binding Domain in Rice. Front Plant Sci. 2022 Apr 25;13:865848. SCI, IF=5.735.
[10]Fu H, Zhao J, Ren Z, Yang K, Wang C, Zhang X, Elesawi IE, Zhang X, Xia J, Chen C, Lu P, Chen Y, Liu H, Yu G, Liu B. Interfered chromosome pairing at high temperature promotes meiotic instability in autotetraploid Arabidopsis. Plant Physiol. 2022 Feb 4;188(2):1210-1228. SCI, IF=7.061.
[11]Fu R, Wang C, Shen H, Zhang J, Higgins JD, Liang W. Rice OsBRCA2 is required for DNA double-strand break repair in meiotic cells. Front Plant Sci. 2020 Nov 16;11:600820. SCI, IF=5.735.
[12]He Y, Wang C, Higgins JD, Yu J, Zong J, Lu P, Zhang D, Liang W. MEIOTIC F-BOX Is Essential for Male Meiotic DNA Double Strand Break Repair in Rice. Plant Cell. 2016, 28: 1879-1893. SCI, IF=11.277.
[13]Fu M, Wang C, Xue F, Higgins J, Chen M, Zhang D, Liang W. The DNA topoisomerase VI–B Subunit OsMTOPVIB Is Essential for Meiotic Recombination Initiation in Rice. Molecular Plant. 2016, Nov 7;9(11):1539-1541. SCI, IF=13.16.
[14]阚婷婷, 汪冲, 郑志仁,张辉. 基因编辑技术在花卉育种中应用的研究进展. 上海师范大学学报.2021,50(1):50-56.
5. 代表性授权专利:
[1]张大兵,梁婉琪,汪冲,袁政,陈明姣,罗治靖. 雄性不育基因OsNIN5及其应用和育性恢复的方法,专利号:CN110938122B,公告日:2022.07.01.
[2]张辉,汪冲,罗鹏宇,洪政,张亚军. 一种CRISPR/Cas9介导的植物多基因编辑载体的构建方法和应用,公开号:CN113564197A,公开日:2021.10.29.
[3]张辉,汪冲,魏闯,贾萌.基于基因编辑技术的GBSSI突变型蛋白及其在植物育种中的应用,公开号:CN112760304A,公开日:2021.05.07.
更新时间:2023年4月