1. 个人简介:
伍晓斌,博士,教授,博士生导师,上海师范大学食品学科带头人和专业负责人。2005年获得中国科大红鹰dhy9999微生物研究所生物化学与分子生物学博士学位。研究领域集中在分子营养、食品安全以及重金属离子代谢。近年来在Mol Aspects Med,Antioxid Redox Signal,J Biol Chem,LWT-Food Science & Technology,Metallomics等期刊以通讯作者或第一作者发表SCI论文多篇。应邀为 BMC genomics, Metallomics等国际期刊审稿百余篇次。主持多项国家省市基金。
研究工作经历:
2015/1-至今: 上海师范大学,大红鹰dhy9999,教授。
2008/2-2014/12:美国内布拉斯加林肯大学,生化系,Senior researcher。
2006/1-2008/1: 西班牙INBIOTEC研究所,博士后。
2. 主要研究方向:
[1] 分子营养与食品安全。
[2] 重金属离子代谢机制及其相关疾病研究。
[3] 抗生素代谢途径调控。
3. 代表性科研项目:
[1] 农产品中重金属快速精准检测试纸条的制备和示范,上海市科技兴农项目,2021-2024
[2]发酵茶加工贮藏过程中微生物菌落结构演替及其生长规律,十三五国家重点攻关项目子课题,2019-2022
[3]铜离子调控表皮生长因子受体蛋白(EGFR)的机制研究,上海市自然科学基金,2016-2018
[4] 上海市高校特聘教授基金,2015-2018
4. 代表性论文及著作:
1. Li J#, Wu J#, Xu N#, Yu Y, Brake J, Xu R, Wu X*. Dynamic evolution and correlation between microorganisms and metabolites during manufacturing process and storage of Pu-erh tea. LWT- Food Science & Technology. 2022, ahead of print.
2. Bian J#, Wang L#, Wu J, Simth N, Zhang L, Wang Y, Wu X*. MTM1 plays an important role in the regulation of zinc tolerance in Saccharomyces cerevisiae. J Trace Elem Med Biol. 2021 Jul;66:126759.
3. Li J#, Xu R#, Zong L, Brake J, Cheng L, Wu J, Wu X*. Dynamic evolution and correlation between metabolites and microorganisms during manufacturing process and storage of Fu brick tea. Metabolites. 2021 Oct;11(10):703.
4. Chen X, Zhang R, Sun J, Simth N, Zhao M, Lee J, Ke Q*, Wu X*. A novel assessment system of toxicity and stability of CuO nanoparticles via copper super sensitive Saccharomyces cerevisiae mutants. Toxicol In Vitro. 2020 Dec;69:104969.
5. Zhang F#, Bian J#, Chen X, Huang J, Smith N, Lu W, Xu Y, Lee J, Wu X*. Roles for intracellular cation transporters in respiratory growth of yeast. Metallomics. 2019 Oct;11(10):1667-1678.
6. Bian J#, Shi X#, Li Q, Zhao M, Wang L, Lee J, Tao M*, Wu X*.A novel functional role of nickel in sperm motility and eukaryotic cell growth. J Trace Elem Med Biol. 2019 Jul; 54:142-149.
7. Wu X, Kim H, Seravalli J, Barycki JJ, Hart PJ, Gohara DW, Di Cera E, Jung WH, Kosman DJ, Lee J*. Potassium and the K+/H+ Exchanger Kha1p promote binding of copper to apoFet3p multi-copper ferroxidase. J Biol Chem. 2016 Apr;291(18):9796-9806.
8. Wei W#, Smith N#, Wu X#, Kim H#, Seravalli J, Khalimonchuk O and Lee J*. YCF1-Mediated Cadmium Resistance in Yeast Is Dependent on Copper Metabolism and Antioxidant Enzymes. Antioxidants & Redox Signaling.2014 Oct 1; 21(10):1475-89.
9. Kim H#, Wu X#, Lee J*. SLC31(CTR) family of copper transporters in health and disease. Mol Aspects Med. 2013 Apr-Jun; 34 (23): 56170.
10. Wu X, García-Estrada C, Vaca I, Martín JF*. Motifs in the C-terminal region of the Penicillium chrysogenum ACV synthetase are essential for valine epimerization and processivity of tripeptide formation. Biochimie. 2012 Feb; 94(2):354-364.
11. Wu X, Sinani D, Kim H, Lee J*. Copper transport activity of yeast Ctr1 is down-regulated via its C terminus in response to excess copper. J Biol.Chem. 2009 Feb; 284(7):4112-4122.
5. 获奖情况:
上海高校特聘教授(2014)
6. 代表性授权专利:
[1]伍晓斌,孙曌月,李晶,吴杰。酿酒酵母和乳酸杆菌在普洱茶发酵中的应用,专利号:202110924751.2
[2] 伍晓斌,黄嘉宇,李晶,许然。一种茶基质培养基及其应用,专利号:202110925443.1
Email: xwu6@shnu.edu.cn
更新时间:2022年1月